| Anesthesia/Analgesia | Anticholinergic | Antiparasitic | Euthanasia |
| Anti-inflammatory | Antibiotics | Miscellaneous | Notes |
| Dose | Comments Back to Top | |
ACETAMINOPHEN (TYLENOL) |
1-2 MG/ML DW (14) // 300 MG/KG IP |
NONSTEROIDAL ANTI-INFLAMMATORY, ANALGESIC |
ACETHYLSALICYLICATE ACID (ASPIRIN) |
120-300 MG/KG PO OR 100-150 MG/KG PO q4h (14) // 25 IP/20 SC/120 PO MG/KG Q4H(2) |
NONSTEROIDAL ANTI-INFLAMMATORY, ANALGESIC |
ACETYLPROMAZINE (ACEPROMAZINE) - DOSAGE |
0.5-1.0 MG/KG IM (14) // 1-2 MG/KG IM |
TRANQUILIZER-PHENOTHIAZINE |
BUPIVACAINE (MARCAINE) |
AS NEEDED |
LOCAL ANESTHETIC |
BUPRENORPHINE (BUPRENEX) |
0.05-0.1 MG/KG IP (1)12//2 MG/KG SC (1) Q12H (2)/(4) 0.05-2.5 MG/KG SC, IP q6-12h (14) (USE 0.05) |
NARCOTIC AGONIST-ANTAGONIST V |
BUTORPHANOL (STADOL OR TORBUTROL) |
1.5 MG/KG SC q2-4h (14) // 5.4 MG/KG SC (1) |
NARCOTIC AGONIST-ANTAGONIST V |
DIAZAPAM (VALIUM) |
5 MG/KG IP // 3-5 MG/KG IM (14) |
TRANQUILIZER - BENZODIAZEPINE IV |
DIAZAPAM - DURATION TO EFFECT |
1-2 HOURS |
TRANQUILIZER - BENZODIAZEPINE IV |
DIAZAPAM - TIME TO EFFECT |
1-2 MIN |
TRANQUILIZER - BENZODIAZEPINE IV |
FENTANYL/DROPERIDOL (INNOVAR-VET)-DOSAGE |
0.3-0.5 ML/KG IM (14) // 2-5 ML/KG (4) |
NEUROLEPTANALGESIC, NARCOTIC/BUTYROPHENONE TRANQUILIZER II |
FENTANYL/ DROPERDOL - DURATION EFFECT |
15-20 MIN |
NEUROLEPTANALGESIC, NARCOTIC/BUTYROPHENONE TRANQUILIZER II |
FENTANYL/DROPERIDOL - TIME TO EFFECT |
2 MIN |
NEUROLEPTANALGESIC, NARCOTIC/BUTYROPHENONE TRANQUILIZER II |
FENTANYL/DROPERIDOL/DIAZEPAM-DOSE |
5 MG/KG DIAZEPAM IP 1ST,/FOLLOWED BY 0.1 ML/30G IP OF 1:10 SALINE DILUTION INNOVAR (1) |
NEUROLEPTANALGESIC, NARCOTIC/BUTYROPHENONE TRANQUILIZER, BUTYROPHENONE II |
| IBUPROFEN | 7-15 MG/KG PO q4h (14) | ANTI-INFLAMMATORY, ANALGESIA |
KETAMINE (KETASET, VETALAR) - DOSAGE |
44 MG/KG IM (14) // 100-200 MG/KG IM (1) |
DISSOCIATIVE |
KETAMINE-ACEPROMAZINE |
100/2.5 MG/KG IM (1)/ (2) |
DISSOCIATIVE/TRANQUILIZER |
KETAMINE-DIAZEPAM (VALIUM) |
200 IM/5 IP MG/KG (1)/ (2) |
DISSOCIATIVE/TRANQUILIZER |
KETAMINE-XYLAZINE (ROMPUN) |
50/5 MG/KG IP (14) // 200 IM/10 IP MG/KG (1)/ (2) 100mgket/20mgxyz/4/6ml sterile water (NIH)=dose 0.1 ml/20g im, ip |
DISSOCIATIVE/ANALGESIC |
MEPERIDINE (DEMEROL) |
20 MG/KG IM SC (14) (1) Q2-3H |
NARCOTIC II, ANALGESIC |
METHOHEXITAL (BREVITAL/BREVANE) |
6 MG/KG IV (2) |
ULTRA SHORT BARBITURATE IV |
MORPHINE |
2-5 MG./KG SC q2-5h (14) // 10 MG/KG IM SC (1) Q2-4H (2) |
NARCOTIC II, ANALGESIC |
NALBUPHINE (NUBAIN) |
4-8 MG/KG IM q3h (14) | NARCOTIC AGONIST-ANTAGONISTS ANALGESIC |
OXYMORPHONE (NUMORPHAN) DOSAGE |
0.2-0.5 MG/KG SC IM q6-12h (14) | NARCOTIC II, ANALGESIC |
PENTAZOCINE (TALWIN-V) |
10 MG/KG SC q2-4h (14)(2) IM IV Q3-4H (2) |
NON-NARCOTIC ANALGESIC IV |
PENTOBARBITAL Na (NEMBUTAL) |
40 MG/KG IV IP SEDATION /50-90 MG/KG IP SURG. ANEST.(14) (1)/ (4) |
BARBITURATE SHORT II, SEDATION, ANESTHETIC (NOT RECOMMENDED -MARGINAL ANALGESIA (14)) |
PHENYLBUTAZONE (BUTAZOLDIN) |
150 MG/KG IP (7) |
NONSTEROIDAL ANTI-INFLAMMATORY |
PROCAINE (NOVOCAIN) |
NEVER |
ANESTHETIC LOCAL |
PROPOFOL (RAPINOVET) |
12-26 MG/KG IV (14) | ANESTHETIC |
THIAMYLAL (SURITAL) |
20-50 MG/KG IV IP//25-50 IV (4) |
BARBITURATE ULTRA SHORT III |
THIOPENTAL (PENTOTHAL) |
30-40 MG/KG IV (2) ONLY (1) //25-50 IV (4) |
BARBITURATE ULTRA SHORT III |
TILETAMINE/ ZOLAZEPAM (TELAZOL) 50MG BASE/ML |
100-160 MG/KG IP IM (1) |
DISSOCIATE/TRANQUILIZER III |
TRIBROMOETHANOL (AVERTIN) (0.25%) |
125 MG/KG IP (1)/0.25% (2) |
ANESTHETIC |
XYLAZINE (ROMPUN)- DOSAGE |
4-8 MG/KG IM |
ALPHA-2-ADRENERGIC AGONIST SEDATIVE, ANALGESIC, MUSCLE RELAXANT |
YOHIMBINE. (YOBINE) |
0.5-1.0 MG/KG IV (14) | XYLAZINE REVERSAL |
ANESTHETIC GAS |
Dose | Comments Back to Top |
HALOTHANE - MAC |
TO EFFECT |
INHALANT |
ISOFLURANE - MAC |
TO EFFECT |
INHALANT |
METHOXYFLURANE - MAC |
TO EFFECT |
INHALANT |
NITROUS OXIDE-MAC |
TO EFFECT |
INHALANT |
| Dose | Comments Back to Top | |
DEXAMETHASONE (AZIUM) |
0.06 MG SC IM IV IP |
STEROID |
PREDNISONE (METICORTIN) |
0.05-0.22 MG SC IM |
STEROID |
| Dose | Comments Back to Top | |
| AMIKACIN | 2-5 MG/KG SC. IM q8-12h(14) | ANTIBIOTIC |
AMOXICILLIN |
100 MG/KG SC IM Q12H(2) |
ANTIBIOTIC |
AMPICILLIN (POLYFLEX) |
20-100 MG/KG PO, SC, IM q12h (14) // 50-150 MG/KG SC Q12H(2) // OR 30 MG/KG IM Q24H (4.5 MG/30 MG)(3) |
BETA LACTAM ANTIBIOTIC |
BACITRACIN |
TOPICAL |
ANTIBIOTIC |
| CARBENICILLIN | 100 MG/KG PO q12h (14) | |
CEPHALORIDINE (LORIDINE) |
10-25 MG/KG SC, IM q24h (14) |
BETA LACTAM ANTIBIOTIC |
CHLORAMPHENICOL PALMITATE (CHLOROMYCETIN) |
DW 0.5 MG/ML(3)(14) |
BACTERIAL STATIC BROAD SPEC. |
CHLORAMPHENICOL SUCCINATE (CHLOROMYCETIN) |
50-200 MG/KG PO q8h OR 30-50 MG/KG SC, IM q24h (14) // 50 MG/KG IM Q12H(2) // OR Q24H (1.5 MG/30 GM)(3) |
BACTERIAL STATIC BROAD SPEC. |
DIHYDROSTREPTOMYCIN |
NEVER |
BACTERIAL |
| DOXYCYCLINE | 2.5MG/KG PO q12h (14) | PNEUMONIA, NOT IN YOUNG OR PREGNANT |
| ENROFLOXACIN | 25-85 MG/KG q24h X 14 DAYS OR 0.05-0.20 MG/ML DW X 14 DAYS(14) | PASTEURELLOSIS |
ERYTHROMYCIN |
20 MG/KG PO (14) | BACTERIAL |
GENTAMICIN (GENTOCIN) |
5 MG/KG SC, IM q24h (14) // 5 MG/KG SC IM SID (0.15 MG/30GM) (3)14D |
AMINOGLYCOSIDES |
GRISEOFULVIN (FULVICIN U/F) |
25-50 MG/KG PO q12h X 14-60 DAYS (14) // 75 MG/KG PO SID 14D// OR 60 MG/KG PO IN FOOD(3) |
ANTIFUNGAL |
| KETOCONAZOLE | 10-40 MG/KG PO q24h X 14 DAYS | SYSTEMIC MYCOSES, CANDIDIASIS |
NEOMYCIN (BIOSOL) |
50 MG/KG SC q24h (14) // 2.6 MG/ML DW (14) |
DIARRHEA |
OXYTETRACYCLINE (LIQUAMYCIN) |
0.4 MG/ML DW(3)(14) // 100 MG/KG SC Q12H(2)// 10-20 MG/KG PO q8h (14) |
BACTERIAL STATIC BROAD SPEC. |
PENICILLIN PROCAINE (AZIMYCIN) |
NEVER |
BACTERIAL |
STREPTOMYCIN (BIOTEC) |
NEVER |
BACTERIAL |
| SULFADIMETHAXINE | 10-15 MG/KG PO q12h (14) | |
SULFAMERAZINE |
1 MG/ML DW (14) // 1 MG/4G FEED (14) |
BACT. COCCIDIA, CIT,B |
| SULFAMETHAZINE | 1 MG/ML DW (14) | |
SULFAQUINOXALINE (SULQUIN) |
1MG/ML DW (14) // 0.025% 30days |
EIMERIA, KLOS. PAST. |
TETRACYCLINES |
100 MG/KG SC SID (3 MG/30 GM)(3) // DW 3 MG/ML(3) |
BACTERIAL STATIC BROAD SPEC//FROG RED LEG |
TRIMETHOPRIM (40MG/ML)/SULPHADOXINE (200MG/ML) (TRIBRISSEN) |
30 MG/KG PO, SC, IM a12h (14) // 0.5 ML/KG SC Q12H(2) |
TRIMETHOPRIM / SULPHONAMIDE |
TYLOSIN |
0.5 MG/ML DW (14) // 10 MG/KG PO, SC, IM q24h (14) // 2-5 MG/ML DW10 MG/KG SC Q12H(2) // OR (0.3 MG/KG GM) IM(3) |
MACROLIDES |
| Dose | Comments Back to Top | |
ATROPINE - DOSAGE |
0.04 MG/KG SC IM(2)/(3)(14) |
ANTICHOLINERGIC |
ATROPINE - DURATION EFFECT |
25 MIN |
ANTICHOLINERGIC |
ATROPINE - TIME TO EFFECT |
10MIN |
ANTICHOLINERGIC |
| Dose | Comments Back to Top | |
DICHLORVOS (TASK) |
250-500 MG/KG FOOD 1D |
ECTOPARASITIC-SYPH, HETER |
DICHLORVOS (VOPONA STRIPS) |
STRIP 48H/WK//OR1 OVER CAGE 24 H/W(3) // Suspend 15 cm above cage x 24 hr, then 2 x /wk x 3 wk (14) |
ECTOPARASITIC |
| DIMETRIDAZOLE | 1 MG/ML DW (14) | GASTROINTESTINAL PROTOZOA |
DITHIAZANINE IODINE |
0.1 MG/KG FOOD 7D |
SYPH. HETER. STRONG.TR |
| FENBENDAZOLE | 0.3% FEED X 14 DAYS (14) // 20 (50 FOR GIARDIASIS) MG/KG PO X 5 DAYS (14) | CESTODES, PINWORMS, GIARDIASIS |
FIPRONIL (FRONTLINE) |
7.5 MG/KG TOP q30-60d (14) | FLEA ADULTCIDE |
IVERMECTIN (IVOMEC) |
0.2 MG/KG PO, SC q7d X 3 WK (14) // 8 MG/L DW X 4 D/WK X 5 WK (14) // 200 MCG/KG PO SC(3) |
MITE, PINWORMS |
MEBENDAZOLE (TELMIN) |
10 MG/KG PO 5D(3) |
NEMATODIASIS COSMOCE |
METRONIDAZOLE (FLAGYL) |
15 MG/KG IP 1X |
GIARDIA |
NICLOSAMIDE (YOMESAN) |
100 MG/KG PO(3) |
CESTODES-HYMENOLEPSIS |
PIPERAZINE CITRATE |
2-5 MG/ML DW X 7 DAYS, OFF 7 DAY, REPEAT (14) // 100 MG/KG PO(3) // 16GM/GAL WATER + 200 ML KARO SYRUP SIDX3, REPEAT IN 2 WKS (8) |
ANTI-NEMATODES-SYPHACIA & HET & PINWORMS |
| PRAZIQUANTEL | 6-10 MG/KG PO (14) // 30 MG/KG PO q14d X 3 TX (14) | CESTODES |
PYRVINIUM PAMOATE |
1.6 MG/KG/D 30D |
SYPH. HETER.ENTEROBIU |
| SULFADIMETHOXINE | 10-15 MG/KG PO q12h (14) | COCCIDIOSIS |
SULFAMERAZINE |
1 MG/ML DW (14) | EIMERIA/COCCIDIOSIS |
THIABENDAZOLE (TBZ; OMIZOLE) |
1 MG/ML DW (14) // 100 MG/KG PO q24h X 5D(14)(3) |
COCCIDIOSIS/ASCARIDIASIS |
| Dose | Comments Back to Top | |
| ATROPINE | 20-40 MG/ANIMAL PO (14) | ANTICHOLINERGIC |
| DEXAMETHASONE | 0.5-2.0 MG/KG PO, SC, DECREASE DOSE q12h X 3-14 DAYS (14) | ANTI-INFLAMMATORY |
| DOXAPRAM | 5-10 MG/KG IP, IV (14) | RESPIRATORY STIMULANT |
| FUROSEMIDE | 5-10 MG/KG SC, IM q12h (14) | DIURETIC/PULMONARY CONGESTION/ASCITES |
| LACTATED RINGER'S SOLUTION | 50-100 ML/KG SC, IV, IO q12h (14) | MAINTENANCE FLUID |
| LOPERAMIDE (IMODIUM A-D) | 0.1 MG/KG PO q8h X 3 DAYS THEN q24h X 2 DAYS (GIVEN IN 1.0 ML WATER)(14) | DIARRHEA |
OXYTOCIN |
0.2-3 UNITS/KG SC IM IV (14)(9) |
DELAYED PARTURITION, UTERINE/MILK HORM. |
| PREDNISONE | 0.5-2.2 MG/KG SC IM (14) | ANTI-INFLAMMATORY |
| VITAMIN B COMPLEX | 0.02-0.20 ML/KG SC IM (14) | |
| VITAMIN D | 200-400 IU/KG SC IM (14) | |
| VITAMIN E/SELENIUM | 0.1ML/100-250 G SC (14) | |
| VITAMIN K1 | 1-10 MG/KG IM q214h X 4-6 DAYS (14) | WARFARIN POISONING |
| EUTHANASIA | Dose | Comments Back to Top |
| Sodium pentobarbital | 150 mg/kg IP | Controlled substance |
| Halothane | To effect | High Concentration, Rapid flow, High flow rates may initially frighten the animal, If a chamber is used Animal should not come into contact with liquid, Animals should not be overcrowded, Animals should be compatible |
| Isoflurane | To effect | High Concentration, Rapid flow, High flow rates may initially frighten the animal, If a chamber is used Animal should not come into contact with liquid, Animals should not be overcrowded, Animals should be compatible |
| CO2 | To effect | No breathing, no heart beat/pulse, no response to toe/ear pinch for at least 2 minutes, Must use a gas cylinder |
| CO | To effect | No breathing, no heart beat/pulse, no response to toe/ear pinch for at least 2 minutes, Very hazardous, Must use a gas cylinder |
| Potassium chloride | 1-2 mmol/kg IV or Intracardiac | Requires general anesthesia |
| Cervical dislocation | Conditionally acceptable | Requires another method |
| Decapitation | Conditionally acceptable | Requires another method |
| Chloral hydrate | Unacceptable | |
| Abbreviations Back to Top | ||
(1)
= Anesthesia and
Analgesia in Laboratory Animals: American College of
Laboratory Animal Medicine: 1990 |
EOD = Every
Other Day SID = Once a day BID = Twice a day (generally every 12 hours) TID = Three times a day (every 8 hours) QID = Four times a day (every 6 hours) Q?H = Every ? hours IM = Intramuscular injection IP = Intraperitoneal injection SC or SQ = Subcutaneous injection IV = Intravenous injection PO = Per Os (By Mouth) (Orally) DW = Drinking water 3DX4 = 3 days of treatment, repeated 4 times |
|
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